More Info

Sceletium tortuosum is a low to the ground flowering creeper that grows almost exclusively in South Africa. For hundreds of years, native tribes prized its calming effects, which appear to be very similar to those of St. John's Wort, except the potency is significantly greater. The plant is nowhere near as common in the wild as it once was, with most of it being grown in controlled environments.

A-Grade Sceletium Tortousum direct from South Africa

Our Sceletium powder is A-Grade, certified organically cultivated and high alkaloid content - typical mesembrine at 1.5% by dry weight.


Buy from the source!

We are sometimes asked why our prices are so reasonable... well, the answer is that we source our Sceletium right here in South Africa - where it grows. South Africa is the natural home of Sceletium and is the place where you can get the highest quality for the best price. 


Sceletium Uses

Benefits and Uses

Tablets and capsules of Sceletium are being used successfully by a number of psychiatrists, psychologists and doctors with excellent results for anxiety states and mild to moderate depression; and they can also be used by the lay public as supplements to elevate mood and for stress and tension.

In addition to Sceletium's common use for the stress and mental fatigue of modern industrial living, Sceletium has been used as a natural supplement for

Mood Upliftment

Decrease of anxiety, stress and tension

Increased Energy

Sceletium elevates mood and decreases anxietystress and tension. It has also been used as an appetite suppressant by shepherds walking long distances in arid areas. In intoxicating doses it can cause euphoria, initially with stimulation and later with sedation. Long-term use in the local context followed by abstinence has not been reported to result in a withdrawal state. The plant is not hallucinogenic, and no severe adverse effects have been documented.

Sceletium is also being used as a natural anti-depressant that is said to be safer than many pharmaceutical alternatives.

Individuals suffering from depression and anxiety can benefit from Sceletium.

Mesembrine works thus:

The brain is made up of countless neurons, which transmit signals to each other only by jumping the gap (synapse) to neighboring neurons. The signal cannot however jump the synapse without assistance.

The message can only travel when the neuron releases a neurotransmitter to fill this gap and allow the signal to transient via it.

The receiving neuron has many points on its surface that which act as potential locks, each of which is known as a receptor and is effected by a particular type of neurotransmitter. When sufficient amounts of the neurotransmitter are received by the relevant receptor, a nerve impulse is started and the message continues to its ultimate destination. To permit recovery of the neuron to receive new messages, the brain takes away the neurotransmitter from the neuron receptors and permitting it to be sent back to the originating nerves, a process known as re-uptake.

In individuals suffering from depression, the neurotransmitter serotonin (also known as 5-hydroxytryptamine) is lacking. Mesembrine slows down the re-uptake process, making it more probable there will be more serotonin in the relevant receptors, greatly increasing the possibility that there will be sufficient levels to set up the signal transfer in all neighboring neurons.

Mesembrine allows the brain to function with reduced levels of serotonin, allowing time for natural levels to build up, whereupon the mesembrine dosage can be reduced or eliminated.